Development of Adenosine Receptor Agonists and Antagonists
نویسندگان
چکیده
منابع مشابه
Adenosine Receptor Antagonists, Agonists, and Allosteric Enhancers
Intense efforts of many pharmaceutical companies and academicians in the A1 adenosine receptor (AR) field have led to the discovery of clinical candidates that are antagonists, agonists, and allosteric enhancers. The A1AR antagonists currently in clinical development are KW3902, BG9928, and SLV320. All three have high affinity for the human (h) A1AR subtype (hA1 Ki < 10 nM),> 200-fold selectivi...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1990
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)32893-8